ORIGINAL CONTRIBUTIONS In Utero Exposure to Background Levels of Polychlorinated Biphenyls and Cognitive Functioning among School-age Children
نویسندگان
چکیده
1 Chemical Exposures and Molecular Biology Branch, Office of Program Development, Division of Extramural Research and Training, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC. 2 Division of Epidemiology, Statistics, and Prevention Research, National Institute of Child Health and Human Development, Rockville, MD. 3 Department of Chemistry, Warren Wilson College, Asheville, NC. 4 Department of Biostatistics, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC. 5 Westat, Inc., Durham, NC. 6 Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC.
منابع مشابه
In utero exposure to background levels of polychlorinated biphenyls and cognitive functioning among school-age children.
Polychlorinated biphenyls (PCBs) are ubiquitous environmental contaminants. In utero exposure to background levels of PCBs has been associated with intellectual impairment among children in most, but not all, studies. The authors evaluated prenatal PCB exposure in relation to cognitive test (intelligence quotient (IQ)) scores on the Wechsler Intelligence Scale for Children at age 7 years. Pregn...
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BACKGROUND In utero exposure to polychlorinated biphenyls, a ubiquitous environmental contaminant, has been linked to adverse effects on neurologic and intellectual function in infants and young children. We assessed whether these effects persist through school age and examined their importance in the acquisition of reading and arithmetic skills. METHODS We tested 212 children, recruited as n...
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Background: Oily fish and their extracted oils may be a source of polychlorinated biphenyls (PCBs) which can induce toxic effects on the consumers. The main aim of this survey was estimation of PCBs intake through fish oil-derived dietary supplements and prescription drugs in the Japanese population. Methods: PCBs levels were determined in 20 fish oil-derived dietary supplements and 6 oil-deri...
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This article reviews the findings in children exposed to various levels of polychlorinated biphenyls (PCBs) and related compounds in utero and early postnatally. Yu-Cheng ("oil-disease") mothers were Taiwanese women exposed to PCBs and their heat-degradation products from the ingestion of contaminated rice oil in 1979. Children of these mothers were born growth retarded, with dysmorphic physica...
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BACKGROUND Organohalogen compounds (OHCs) are known to have neurotoxic effects on the developing brain. OBJECTIVE We investigated the influence of prenatal exposure to OHCs, including brominated flame retardants, on motor, cognitive, and behavioral outcome in healthy children of school age. METHODS This study was part of the prospective Groningen infant COMPARE (Comparison of Exposure-Effec...
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